Enzon and INEX form partnership for oncology therapy.(Enzon Pharmaceuticals, Inc., Inex Pharmaceuticals Corporation)
Publication Date: 01-FEB-04
Publication Title: BIOTECH Patent News
Format: Online
Company: Enzon Pharmaceuticals Inc.~Alliances and partnerships Enzon Pharmaceuticals Inc.~Product development Inex Pharmaceuticals Corp.~Alliances and partnerships Inex Pharmaceuticals Corp.~Product development

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Description

Enzon Pharmaceuticals, Inc. (Bridgewater, NJ) and Inex Pharmaceuticals Corporation (Vancouver, Canada) announced a strategic partnership to develop and commercialize INEX's proprietary oncology product Onco TCS.

Under the terms of the agreement, Enzon receives the exclusive North American commercialization rights for Onco TCS for all indications. The lead indication is relapsed aggressive non-Hodgkin's lymphoma (NHL) for which INEX is in the process of submitting a "rolling" New Drug Application (NDA) to the United States Food and Drug Administration (FDA), which is expected to be completed during the first quarter of calendar year 2004. The product is also in numerous phase II clinical trials for several other cancer indications, including first-line NHL.

INEX receives a US$12 million up-front payment and will receive up to a US$20 million payment upon Onco TCS receiving approval from the FDA. Additional development milestones and sales based bonus payments could total US$43.75 million, of which US$10 million is payable upon annual sales first reaching US$125 million and US$15 million is payable upon annual sales first reaching US$250 million. INEX will also receive a percentage of commercial...



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