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Description
Design & Participants: Randomized, double-blind, placebo-controlled trial of 50 healthy, adult volunteers (19 female and 31 male; mean age of 33 [+ or -] 7.7 years)
Study Medication & Dosage: One capsule containing 1 x 1010 cfu of Lactobacillus fermentum CECT5716 or placebo. The influenza vaccine contained inactivated influenza (A/New Caledonia/20/99[H1N1], A/Fujinan/411/2002[H3N2], B/Shanghai/361/2002[B]).
Duration: The study consisted of 28 days of probiotic treatment. Each volunteer received the intramuscular vaccination at day 14.
Outcome Measures: The primary endpoint of the study was the immune response induced... |
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