ROSETTA/WEIZMAN INSTITUTE IDENTIFY ROLE OF MICRORNA.
Publication Date: 01-AUG-07
Publication Title: Worldwide Biotech
Format: Online

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Description

Rosetta Genomics Ltd, (Nasdaq:ROSG), North Brunswick, N.J. a leading microRNA company, announced today research published in the journal Molecular Cell by scientists from the Weizmann Institute of Science and Rosetta Genomics . The findings suggest the potential for a specific, single microRNA (miR-34a) to be used as a drug candidate in cancer therapy to increase programmed cell-death (apoptosis) in the context of the potent tumor suppressor p53.

p53 has been widely accepted as a powerful tumor inhibitor that can prevent or slow the spread of cancer cells by facilitating apoptosis. In this study, activation of p53 in-vivo in mice as well as in cultured human cells induced the expression of a...

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