Klotho Inc.

Researchers from Kyoto University detail findings in metabolism.(Report)
Biotech Week; 11/18/2009; 956 words; ...Moreover, TBP2 expression was increased significantly in klotho-deficient mice, which exhibit a syndrome resembling aging...journal Antioxidants & Redox Signaling is: Mary Ann Liebert Inc., 140 Huguenot Street, 3RD FL, New Rochelle, NY 10801...

New obesity and diabetes study findings have been reported by researchers at Amgen, Inc.
Obesity & Diabetes Week; 10/26/2009; 1145 words; ...region responsible for beta Klotho interaction. We determined that beta Klotho-dependent FGFR1c, 2c, and...activation were abolished, and beta Klotho-independent FGFR4 activation...Wu and colleagues, Amgen, Inc. The researchers concluded...

Researchers from Osaka University describe findings in life sciences.(Report)
Biotech Week; 8/5/2009; 771 words; "Klotho is a senescence suppressor protein...The researchers concluded: "Klotho may have a role in the modulation...published their study in Endocrine (Klotho suppresses TNF-alpha-induced...contacted at: Humana Press Inc., 999 Riverview Drive Suite...

Studies from R. Micanovic et al in the area of cellular physiology described.
Science Letter; 6/2/2009; 998 words; ...decreased affinity for beta Klotho. By contrast, removal of up...on the interaction with beta Klotho. Terminal deletions had greater...terminus is important for beta Klotho interaction whereas the N...Division John Wiley & Sons Inc., 111 River St., Hoboken...

Amgen, Inc. publishes research in biotechnology business.
Biotech Week; 2/25/2009; 737 words; ...of FGF21 had no impact on b-Klotho binding. Interestingly, several...Yie and colleagues, Amgen, Inc. The researchers concluded...critical for binding to b-Klotho and the N-terminus is critical...contact J.M. Yie, Amgen Inc., Dept. of Metab Disorders...