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Vertical transmission rate is low when pregnant women get HIV therapy.

Publication: Perspectives on Sexual and Reproductive Health
Publication Date: 01-SEP-08 		Format: Online
Delivery: Immediate Online Access
Full Article Title: Vertical transmission rate is low when pregnant women get HIV therapy.(Digests)(human immunodeficiency virus)(Clinical report)

Article Excerpt
In a national surveillance study of singleton births to HIV-infected women in the United Kingdom and Ireland, the rate of mother-to-child HIV transmission was 1.2% overall, and 0.8% for women who had received antiretroviral therapy for at least the last 14 days of pregnancy. 1 Transmission rates were 0.7% for women who had received highly active antiretroviral therapy (HAART) and had either a planned cesarean section or a planned vaginal delivery, and 0.0% for those who had received zidovudine monotherapy and had a planned cesarean delivery. After adjustment for maternal HIV viral load, delivery mode and infant's sex, each additional week of HAART was associated with a reduced risk of HIV transmission (odds ratio, 0.9).

Because HAART, appropriate management of delivery and avoidance of...

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