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BAYER EXPANDS HEMOPHILIA PORTFOLIO FEATURING MAXY-VII.

Publication: Biotech Business
Publication Date: 01-AUG-08 		Format: Online
Delivery: Immediate Online Access
Full Article Title: BAYER EXPANDS HEMOPHILIA PORTFOLIO FEATURING MAXY-VII.(Company overview)

Article Excerpt
Bayer HealthCare is expanding its commitment to hemophilia with the acquisition of Maxygen's hemophilia program assets, including a next-generation recombinant Factor VIIa protein known as MAXY-VII. The lead therapeutic candidate is expected to enter Phase 1 clinical testing in the third quarter of 2008. The total transaction is valued at US-Dollar 90 million upfront with a final, potential milestone payment of US-Dollar 30 million. This agreement includes a license to use Maxygen's MolecularBreeding(tm) technology, a novel research platform, for exploiting gene targets.

Hemophilia is an inherited bleeding disorder caused by deficient or defective blood coagulation proteins. Roughly 20 to 30 percent of patients with hemophilia develop antibodies - or inhibitors - to current therapies. In these instances a Factor VIIa is used to bypass inhibitors and help these individuals to form clots. MAXY-VII is a next generation Factor VIIa clotting...

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