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What is causing this woman's dry cough?

Publication: Journal of Respiratory Diseases
Publication Date: 01-JUN-08
Format: Online
Delivery: Immediate Online Access
Full Article Title: What is causing this woman's dry cough?(DIAGNOSTIC PUZZLERS: Challenging cases to test your clinical skills)(Case study)

Article Excerpt
A 39-year-old woman presented with dry cough, which she had had for 3 months. She had mild intermittent asthma and a 5 pack-year smoking history. Her symptoms started after an upper respiratory tract infection and persisted despite multiple courses of antibiotics, decongestants, and corticosteroids.

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The patient experienced episodes of pleuritic chest pain, shortness of breath with exertion, and generalized malaise. This was accompanied by low-grade fevers and night sweats. She reported losing 10 lb during this time. She denied recent history of any sick contacts or travel and had no known exposure to allergens or toxic fumes, but she had had a pet dog and a turtle for many years. Her mother had died of lung cancer at 39 years of age.

Her physical examination findings were remarkable for crackles in the left upper zone. Complete blood cell count revealed leukocytosis (leukocyte count, 20,500/[micro]L), anemia (hemoglobin level, 8.5 g/dL), and thrombocytosis (platelet count, 608,000/[micro]L), and her erythrocyte sedimentation rate was elevated. HIV and purified protein derivative test results were negative, and the sputum...

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