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...healing rates diabetic foot ulcers between honey and the conventional dressing, and the honey had no significant effect on glycaemic control. It was concluded that honey is at least as effective as conventional dressings in healing diabetic foot ulcers.
Amputations are common following diabetic foot ulceration. A main aim of the diabetic foot care clinic in the University of Malaya Medical Centre in Kuala Lumpur, Malaysia, is to prevent and treat diabetic foot ulcers so that amputation rates are reduced. Conventional dressings are used in most cases, but honey-based ones have also been used and are claimed to be better than a conventional dressing by many of its proponents.
A systematic review by Moore et al (2001) found seven randomised trials on the use of honey in the treatment of burns or wounds. Six of the studies were conducted by the same researcher (Subrahmanyam 1991, 1993, 1994, 1996, 1998, 1999). Although the studies in the review were of limited quality, six of the seven showed honey to be superior for wound healing. A more recent review (Molan, 2006) quoted .positive findings in 17 randomized controlled trials on the use of honey in various wounds. Reports of honey being used to treat a variety of wounds ranging from various wounds in infants to post-vulvectomy wounds also give credence to the therapeutic use of honey (Cavanagh et al, 1970; Efem, 1993; Vardi et al, 1998).
The wound healing properties of honey have been attributed to various factors, including antibacterial action and endogenous antiseptic properties (Zumla and Lulat, 1989; Harris, 1994; Lione, 1998; Subrahmanyam, 1998; Cooper and Molan, 1999).
However, to date, no formal randomised controlled trial on the use of honey in diabetic foot ulcers have been published.
Aim of the study
This study's objective was to ascertain whether honey was a viable dressing for diabetic foot ulcers. The effect of the use of honey on glycaemic control in people with diabetes was also investigated.
Materials and method
Selection of participants
This study was carried out on people with diabetic foot ulcers who attended the Wound Management Centre of the University of Malaya Medical Centre (UMMC), which is a teaching hospital. The majority of these people were referred from the hospital's diabetic clinic and primary care clinic. The approval of the hospital's medical ethics committee was obtained before the study was carried out. Funding was obtained from a short-term research grant provided by the University of Malaya.
People with diabetic ulcers who met the following criteria were included in the study:
* age 40 years or more, with previously known diabetes mellitus.
*...
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