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Concise abstracts of papers in the literature chosen for significance to clinical practice -- Using argatroban in the elderly and the obese: Results of 2 studies.

Publication: Journal of Respiratory Diseases
Publication Date: 01-OCT-07
Format: Online
Delivery: Immediate Online Access

Article Excerpt
Bartholomew JR, Pietrangeli CE, Hursting MJ, The Cleveland Clinic. Argatroban anticoagulation for heparin-induced thrombocytopenia in elderly patients. Drugs Aging. June 2007;24:489-499.

Hursting MJ, Jang IK, Clinical Science Consulting, Austin, Texas. Effect of body mass index on Argatroban therapy during percutaneous coronary intervention. J Thromb Thrombolysis. May 28, 2007; [Epub ahead of print].

These 2 studies focused on argatroban dosage considerations in 2 different groups: the elderly and the obese.

-Elderly patients: In light of the reduced clearance of argatroban in elderly persons, Bartholomew and associates set out...

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