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Exelon patch: rivastigmine transdermal system.

Publication: Formulary
Publication Date: 01-SEP-07 		Format: Online
Delivery: Immediate Online Access
Full Article Title: Exelon patch: rivastigmine transdermal system.(New molecular entity)

Article Excerpt
NOVARTIS

Transdermal formulation of cholinesterase inhibitor approved for the treatment of mild-to-moderate dementia of the AD type and mild-to-moderate dementia associated with PD

The precise mechanism of action of the reversible cholinesterase inhibitor rivastigmine is unknown, but it has been suggested that the agent exerts its therapeutic effect by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by cholinesterase, thus enhancing cholinergic function. Rivastigmine was previously available in capsule and oral solution formulations. This...

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