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Individual Differences Caused by Shuffled Chunks of DNA in the Human Genome.

Publication: M2 Presswire
Publication Date: 28-SEP-07
Format: Online
Delivery: Immediate Online Access

Article Excerpt
M2 PRESSWIRE-28 September 2007-YALE UNIVERSITY: Individual Differences Caused by Shuffled Chunks of DNA in the Human Genome(C)1994-2007 M2 COMMUNICATIONS LTD

RDATE:27092007

New Haven, Conn. -- A study by Yale researchers offers a new view of what causes the greatest genetic variability among individuals -- suggesting that it is due less to single point mutations than to the presence of structural changes that cause extended segments of the human genome to be missing, rearranged or present in extra copies.

"The focus for identifying genetic differences has traditionally been on point mutations or SNPs -- changes in single bases in individual genes," said Michael Snyder, the Cullman Professor of Molecular, Cellular & developmental Biology and senior author...

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