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...microRNA (miR-34a) used as drug candidate in cancer therapy to increase programmed cell-death (apoptosis) in the context of the potent tumor suppressor p53.
p53 has been widely accepted as a powerful tumor inhibitor that can prevent or slow the spread of cancer cells by facilitating apoptosis. In this study, activation of p53 in-vivo in mice as well as in cultured human cells induced the expression of a...
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