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Pharmaxis Enrols First Patient in Phase III Bronchiectasis Trial.

Publication: PR Newswire
Publication Date: 19-APR-06 		Format: Online
Delivery: Immediate Online Access

Article Excerpt
SYDNEY, Australia, April 19 /Xinhua-PRNewswire-FirstCall/ -- Specialist pharmaceutical company Pharmaxis Ltd is pleased to announce that the first of 350 patients has enrolled in its Phase III Bronchitol trial to treat the chronic obstructive lung disease, bronchiectasis; an incurable, degenerative and chronic inflammatory condition of the lungs affecting more than half a million people worldwide.

The trial will investigate the safety and effectiveness of Bronchitol in the treatment of bronchiectasis. It is being conducted at 22 hospitals across Australia, New Zealand, the United Kingdom and Northern Ireland. Two thirds of trial volunteers will receive Bronchitol and the remaining one third will receive a placebo. Patients will be assessed for mucus clearance and quality of life as measured by symptoms, cough severity, exercise capacity and lung function.

This trial follows a successful Phase II study in patients with bronchiectasis and the trial design has been constructed following meetings with the European regulatory agencies.

Alan Robertson, Pharmaxis Chief Executive Officer said, ''This pivotal trial...

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