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DURECT Announces Positive Preliminary Results From Its Phase II Study for Its Post-Operative Pain Relief Depot.

Publication: PR Newswire
Publication Date: 18-OCT-05 		Format: Online
Delivery: Immediate Online Access

Article Excerpt
CUPERTINO, Calif., Oct. 18 /PRNewswire-FirstCall/ -- DURECT Corporation announced today positive preliminary results from the Phase II dose escalation study (Cohorts 1-3) in hernia patients in Australia for DURECT's post-operative pain relief depot, SABER(TM)-Bupivacaine. SABER-Bupivacaine is based on DURECT's patented SABER delivery technology and is intended to be administered around the surgical site after surgery to provide 3 days or more of regional pain relief. These results were presented to a group of surgeons attending the American College of Surgeons conference in San Francisco, CA.

(Photo: NewsCom: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO )

"We observed clear dose proportional pharmacokinetics in this study whilst giving a continuous and stable delivery of bupivacaine over a period of four days, with safety was demonstrated across all observed doses. Additionally, this study provides promising...



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