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HYBRIDON'S OLIGONUCLEOTIDES SHOW POTENT ADJUVANT ACTIVITY.

Publication: Biotech Business
Publication Date: 01-SEP-04 		Format: Online - approximately 420 words
Delivery: Immediate Online Access

Article Excerpt
Hybridon, Inc. (AMEX: HBY), Cambridge, Mass., has presented preclinical results illustrating that its 2nd generation immunomodulatory oligonucleotide (IMO) compounds demonstrated potent adjuvant activity, inducing Th1-type mucosal immune responses in mice following oral administration. Th1-type immune responses are important in protecting against infectious diseases and boosting antibody formation.

"These results indicate the improved stability of our novel IMO structures in the gut facilitates...

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