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Agensys Announces IND Submission for Monoclonal Antibody AGS-PSCA for Cancers of Prostate, Pancreas, Bladder.

Publication: Business Wire
Publication Date: 30-JUN-05
Format: Online
Delivery: Immediate Online Access

Article Excerpt
SANTA MONICA, Calif. -- Agensys, Inc. (www.agensys.com) announced today the submission of an Investigational New Drug Application (IND) with the U.S. Food and Drug Administration (FDA) to initiate a Phase 1 clinical trial with AGS-PSCA. AGS-PSCA is a fully human monoclonal antibody (MAb) with therapeutic potential in patients with prostate, pancreatic, and bladder cancers. Agensys plans to focus the initial Phase 1 clinical trial on patients with advanced prostate cancer.

AGS-PSCA is a high affinity, human IgG1k MAb directed to Agensys' proprietary target Prostate Stem Cell Antigen (PSCA). It was generated using XenoMouse(R) technology through a licensing agreement with Abgenix (Nasdaq:...

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