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Amylin and Lilly Announce Encouraging Results From Open-Label Study of AC2993 (Synthetic Exendin-4) in People With Type 2 Diabetes.

Publication: PR Newswire
Publication Date: 18-DEC-02
Format: Online
Delivery: Immediate Online Access

Article Excerpt
Amylin Pharmaceuticals, Inc. and Eli Lilly and Company today announced initial results from 19 patients in an ongoing open-label study of AC2993 (synthetic exendin-4). Patients in the study showed progressive reductions in HbA1c, achieving a mean reduction of 1.5% at twelve weeks, with no indication of a waning of effect over time. HbA1c is a measure of a person's average blood glucose over a period of approximately three months. No increase in body weight was observed. The most common adverse event reported was nausea, consistent with previous AC2993 clinical studies.

These results were observed in 19 people with type 2 diabetes (HbA1c greater than or equal to 7.5% at entry) who were inadequately controlled with...

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