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Antimicrobial drug-resistant Salmonella Typhimurium (Reply to Dahl).

Publication: Emerging Infectious Diseases
Publication Date: 01-OCT-03 		Format: Online
Delivery: Immediate Online Access
Full Article Title: Antimicrobial drug-resistant Salmonella Typhimurium (Reply to Dahl).(Letters)

Article Excerpt
In Reply to Dahl: The emergence and spread of multidrug-resistant Salmonella enterica serovar Typhimurium DT104 (MDR DT104) contributed to an international increase in antimicrobial drug resistance in S. Typhimurium in the late 1990s (1,2). This type of Salmonella is usually resistant to five drugs: ampicillin, chloramphenicol, streptomycin, sulfonamides, and tetracycline (R-type ACSSuT) and easily acquires resistance to other drugs, including quinolones, trimethoprim, and aminoglycosides (1,3-5). To determine death rates after infection with MDR DT104 or closely related strains, we identified patients who were infected with strains at least resistant to ACSSuT (6). Analysis limited to strains that were only R-type ACSSuT would have given a misleading result since MDR DT104 often, as mentioned, develops additional resistance to other classes of antimicrobial drugs in addition to the ACSSuT-complex. This fact needs to be taken into account in any attempt to quantify the overall public health impact of MDR...

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