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Do nasal decongestants relieve symptoms?

Publication: Journal of Family Practice
Publication Date: 01-SEP-03 		Format: Online
Delivery: Immediate Online Access
Full Article Title: Do nasal decongestants relieve symptoms?(Clinical inquiries: from the Family Practice Inquries Network)

Article Excerpt
* EVIDENCE-BASED ANSWER

Oral and topical nasal decongestants result in a statistically significant improvement in subjective symptoms of nasal congestion and objective nasal airway resistance in adults' common colds (strength of recommendation [SOR]: A, based on randomized controlled trials). Evidence is lacking to support the use of decongestants in acute sinusitis.

* EVIDENCE SUMMARY

Nasal congestion is the most common symptom of the common cold, and hundreds of millions of dollars are spent annually on decongestants. A Cochrane review of 4 randomized controlled trials compared single doses of oxymetazoline, pseudoephedrine, and phenylpropanolamine. (1) Included studies involved from 30 to 106 participants, were double-blinded and placebo-controlled, used either topical...

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