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Oral topiramate effective for alcoholism.

Publication: Journal of Family Practice
Publication Date: 01-SEP-03
Format: Online - approximately 762 words
Delivery: Immediate Online Access
Full Article Title: Oral topiramate effective for alcoholism.(Patient Oriented Evidence That Matters)

Article Excerpt
Johnson BA, Ait-Daoud N, Bowden CL, et al. Oral topiramate for treatment of alcohol dependence: a randomized controlled trial. Lancet 2003; 361:1677-1685.

* PRACTICE RECOMMENDATIONS

Oral topiramate is effective in the treatment of alcohol dependence. Patients taking topiramate consumed less alcohol, had fewer heavy drinking days, and had more days abstinent within a 12-week period. This medication adds a significant adjunct to our current treatment of alcoholism and can be considered for use in treating those alcoholics who desire sobriety.

* BACKGROUND

Alcohol dependence is a fairly common problem seen in family practice. To date, there have been few, if any, effective medications that help patients control or reduce their drinking behavior.

Topiramate...

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