...serious is this and should I switch drugs?

A: It's not possible from the information available right now to say how serious this is, but liver complications are never to be taken lightly. Although your medications might be toxic to the liver, you have been on them for a while and they have apparently not given you any problems before now. I would first, then, look to other possible explanations. You should have been tested for past and/or present infection by hepatitis-causing viruses as part of your initial medical assessment. If you had no prior infection by hepatitis A or B, you should have been vaccinated against these. Past infection by hepatitis C often means current infection also, so these results should all be checked. If you weren't vaccinated you may have been already immune,...

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