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New data from University of Miami, Medical Department illuminate research in yersinia.

Publication: Medical Letter on the CDC & FDA
Publication Date: 15-NOV-09 		Format: Online
Delivery: Immediate Online Access

Article Excerpt
According to recent research published in the Journal of Biological Chemistry, "The Yersinia protein kinase A (YpkA) and outer protein J (YopJ) are co-expressed from a single transcript and are injected directly into eukaryotic cells by the plague bacterium Yersinia pestis. When overexpressed in vertebrate or yeast cells, YpkA disrupts the actin-based cytoskeletal system by an unknown mechanism, whereas...



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