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New jervell and lange-nielsen syndrome study results from University of Cambridge described.

Publication: Biotech Week
Publication Date: 07-OCT-09
Format: Online
Delivery: Immediate Online Access

Article Excerpt
"KCNE1 encodes the beta-subunit of the slow component of the delayed rectifier K+ current. The Jervell and Lange-Nielsen syndrome is characterized by sensorineural deafness, prolonged QT intervals, and ventricular arrhythmogenicity," scientists in Cambridge, the United Kingdom report (see also Jervell and Lange-Nielsen Syndrome).

"Loss-of-function mutations in KCNE1 are implicated in the JLN2 subtype. We recorded left ventricular epicardial and...

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