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Disappointing clinical trial pummels Acadia: data suggests drug could have other applications.

Publication: San Diego Business Journal
Publication Date: 14-SEP-09
Format: Online
Delivery: Immediate Online Access
Full Article Title: Disappointing clinical trial pummels Acadia: data suggests drug could have other applications.(BIOTECH)(Acadia Pharmaceuticals Inc.)

Article Excerpt
Acadia Pharmaceuticals planned to have the first drug on the market to treat Parkinson's disease psychosis, which causes hallucinations and delusions for 40 percent of the 1.5 million people living with the disease.

What it didn't plan for was stronger-than-anticipated placebo effects in patients enrolled in the late-stage trial, results that proved its drug ineffective against a placebo.

Acadia's stock fell sharply on the news that its drug candidate, pimavanserin, failed to prove effective in the six-week, 300-person study. Shares of Acadia, traded on Nasdaq as ACAD, lost two-thirds of their value Sept. 1 to close at $2. The stock's 52-week...

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