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Advanced Life Sciences' Restanza Demonstrates Efficacy in Plague Pivotal Animal Study.

Publication: PR Newswire
Publication Date: 29-SEP-09 		Format: Online
Delivery: Immediate Online Access

Article Excerpt
CHICAGO, Sept. 29 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. (BULLETIN BOARD: ADLS) , today announced positive top-line results from a pivotal, non-human primate study involving its novel, once-a-day, oral antibiotic Restanza(TM) (cethromycin) demonstrating statistical significance at a 90% survival rate against an inhaled lethal dose of plague. The study tested Restanza's protective efficacy at various doses up to 64 mg/kg, where nine out of ten animals in the study that received a 14-day course of Restanza initiated within 24 hours after exposure to a lethal dose of plague survived while only one out of ten of the animals that received placebo survived.

(Photo: http://www.newscom.com/cgi-bin/prnh/20080218/ALSLOGO)

Known as the "black death," a plague epidemic decimated Europe in the Middle Ages, killed more than 10 million people in India a century ago and today mainly affects people who come into contact with infected rodents. In weaponized...

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