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Investigators at Astellas Pharma, Inc. publish new data on liquid chromatography.

Publication: Biotech Week
Publication Date: 23-SEP-09
Format: Online
Delivery: Immediate Online Access

Article Excerpt
"(-)-N-{2-[[R]-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758) is a novel inhibitor of the '' funny'' If current channel (If channel) that is expressed in the sinus node of heart and is being developed as a treatment for stable angina and atrial fibrillation. Its metabolites were identified in human urine, plasma, and feces by radio-high-performance liquid chromatography and liquid chromatography-tandem mass spectrometry analyses after oral...

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