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Reports on enzyme research findings from R. Gozalbes and co-researchers provide new insights.

Publication: Medical Letter on the CDC & FDA
Publication Date: 20-SEP-09
Format: Online
Delivery: Immediate Online Access

Article Excerpt
"A combined strategy based on the development of pharmacophore hypotheses and NMR approaches is reported for the identification of novel inhibitors of heparanase, a key enzyme involved in tumor metastasis through the remodeling of the subepithelial and subendothelial basement membranes, resulting in the dissemination of metastatic cancer cells," scientists writing...

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