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National Heart Lung and Blood Institute details research in fabry disease.

Publication: Biotech Week
Publication Date: 29-JUL-09
Format: Online
Delivery: Immediate Online Access
Full Article Title: National Heart Lung and Blood Institute details research in fabry disease.(Report)

Article Excerpt
Research findings, 'Synthesis and characterization of a new fluorogenic substrate for alpha-galactosidase,' are discussed in a new report. "Alpha-galactosidase A hydrolyzes the terminal alpha-galactosyl moieties from glycolipids and glycoproteins in lysosomes. Mutations in alpha-galactosidase cause lysosomal accumulation of the glycosphingolipid, globotriaosylceramide, which leads to Fabry disease," scientists writing in...

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