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Changing the cardiovascular prevention game.

Publication: Harvard Health Letter
Publication Date: 01-JAN-09 		Format: Online
Delivery: Immediate Online Access

Article Excerpt
Changing the cardiovascular prevention game

Results from a large clinical trial may mean a new era of super-low LDL targets and anti-inflammatory strategies.

Commentators on the presidential debates in the fall of 2008 were often asked whether they had spotted any "game changers" * something the candidates said or did that would alter the course of the election. A few days after Election Day, many doctors (especially cardiologists) were talking about a game changer in how we go about preventing heart attacks and strokes.

They were reacting to results from a large clinical trial that showed cardiovascular events were cut in half by taking a powerful statin drug among people whose "bad" LDL cholesterol levels were fine, according to current guidelines, and in no need of lowering. What's more,...

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