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Treatment for early prostate cancer not better than "wait and see".

Publication: HealthFacts
Publication Date: 01-MAR-09
Format: Online
Delivery: Immediate Online Access

Article Excerpt
A common treatment given to men with early-stage prostate cancer--one that has significant harms--was found to be no more effective in extending life than the "wait-and-see" approach. The study, published last summer in the Journal of the American Medical Association, highlights the fact that doctors have been using this treatment for decades without proof of benefit. Its finding became the centerpiece for an unusual article in a recent issue of the Journal of the National Cancer Institute that candidly discussed the many reasons for overuse, chief among them are the financial incentives that encourage treatment ... but more on that later.

The treatment in question is called androgen deprivation therapy (ADT), aka drugs that shut off the male hormones known to promote tumor growth. It is given to men whose cancer is confined to the prostate and received no other treatment, such as surgical removal of the prostate. The 2008 study...

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